Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study.

Atherosclerosis - 1 Aug 2015

Pokharel Yashashwi, Sun Wensheng, Polfus Linda M, Folsom Aaron R, Heiss Gerardo, Sharrett A Richey, Boerwinkle Eric, Ballantyne Christie M, Hoogeveen Ron C

Abstract excerpt

OBJECTIVE: Lipoprotein-associated phospholipase A2 (LpPLA2) activity was associated with higher CHD risk in a meta-analysis, which was partly dependent on circulating lipid levels. Apolipoprotein C3 loss-of-function (ApoC3 LOF) mutations were related with reduced postprandial lipemia and CHD risk. However, the association of LpPLA2 activity with ApoC3 LOF is not known. METHODS: We examined the association of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
Share to Apolipoprotein C-III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atherosclerosis

Share to Dyslipidemias

Share to Lipoprotein Lipase

Share to Postprandial Period

Share to Proportional Hazards Models

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 26117401
DOI: 10.1016/j.atherosclerosis.2015.06.033
PMCID: PMC4731876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study.PMID 26117401Read ↗

Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC).Semantic proximity Read ↗

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.Semantic proximity Read ↗

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.Semantic proximity Read ↗

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.Semantic proximity Read ↗

Joint Associations of APOC3 and LDL-C-Lowering Variants With the Risk of Coronary Heart Disease.Semantic proximity Read ↗

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults.Semantic proximity Read ↗

Loss-of-function mutations in APOC3 and risk of ischemic vascular disease.Semantic proximity Read ↗

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.Semantic proximity Read ↗

LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization studySemantic proximity Read ↗

Coronary Heart Disease and Genetic Variants with Low Phospholipase A<sub>2</sub> ActivitySemantic proximity Read ↗

Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study.Semantic proximity Read ↗

Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.