Article
Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC).
Atherosclerosis - 1 Jan 2018
Garg Parveen K, Norby Faye L, Polfus Linda M, Boerwinkle Eric, Gibbs Richard A, Grove Megan L, Folsom Aaron R, Garimella Pranav S, Matsushita Kunihiro, Hoogeveen Ron C, Ballantyne Christie M
Abstract excerpt
BACKGROUND AND AIMS: Results from prospective studies evaluating the relationship between elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) activity and incident peripheral arterial disease (PAD) have been mixed. We investigated whether higher Lp-PLA2 levels are associated with increased risk of incident PAD and whether PLA2G7 gene variants, which result in lower Lp-PLA2 levels, are associated with...
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