Article
Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson's Disease in Han Chinese.
Chinese medical journal - 5 Jul 2015
Chen Ya-Fang, Chen Wan-Jin, Lin Xiao-Zhen, Zhang Qi-Jie, Cai Jiang-Ping, Liou Chia-Wei, Wang Ning
Abstract excerpt
BACKGROUND: Mitochondrial dysfunction is linked to the pathogenesis of Parkinson's disease (PD). However, the precise role of mitochondrial DNA (mtDNA) variations is obscure. On the other hand, mtDNA haplogroups have been inconsistently reported to modify the risk of PD among different population. Here, we try to explore the relationship between mtDNA haplogroups and sporadic PD in a Han Chinese population....
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