Article
Female genetic distribution bias in mitochondrial genome observed in Parkinson's Disease patients in northern China.
Scientific reports - 25 Nov 2015
Chu Qiaohong, Luo Xiaoguang, Zhan Xiaoni, Ren Yan, Pang Hao
Abstract excerpt
Genetic polymorphisms associated with susceptibility to Parkinson's disease (PD) have been described in mitochondrial DNA (mtDNA). To explore the potential contribution of mtDNA mutations to the risk of PD in a Chinese population, we examined the linkage relationship between several single nucleotide polymorphisms (SNPs) and haplotypes in mtDNA and PD. We genotyped 5 SNPs located on coding genes using PCR-RFLP...
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