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Mitochondrial DNA Haplogroups and Three Independent Polymorphisms have no Association with the Risk of Parkinson's Disease in East Indian Population.

Neurology India - 1 Jan 2000

Saha Tania, Roy Somrita, Chakraborty Rajashree, Biswas Arindam, Das Shyamal K, Ray Kunal, Ray Jharna, Sengupta Mainak

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is a multifaceted illness affecting ~ 0.3% of the world population. The genetic complexity of PD has not been, fully elucidated. Several studies suggest that mitochondrial DNA variants are associated with PD. OBJECTIVE: Here, we have explored the possibility of genetic association between mitochondrial haplogroups as well as three independent SNPs with PD in a representative...

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Identifiers

PMID: 33904476
DOI: 10.4103/0028-3886.314553

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