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Article

SWAP-70 contributes to spontaneous transformation of mouse embryo fibroblasts.

Experimental cell research - 15 Jul 2016

Chang Yu-Tzu, Shu Chung-Li, Lai Jing-Yang, Lin Ching-Yu, Chuu Chih-Pin, Morishita Kazuhiro, Ichikawa Tomonaga, Jessberger Rolf, Fukui Yasuhisa

Abstract excerpt

Mouse embryo fibroblasts (MEFs) grow slowly after cultivation from animals, however, after an extended period of cultivation, their growth accelerates. We found that SWAP-70 deficient MEFs failed to increase growth rates. They maintain normal growth rates and proliferation cycles for at least 5 years. Complementing SWAP-70 deficiency in one of these MEF clones, MEF1F2, by expressing human SWAP-70 resulted in fast...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26103139
DOI: 10.1016/j.yexcr.2015.06.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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