Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SWAP-70 identifies a transitional subset of actin filaments in motile cells.

Molecular biology of the cell - 1 Aug 2003

Hilpelä Pirta, Oberbanscheidt Pia, Hahne Penelope, Hund Martin, Kalhammer Georg, Small J Victor, Bähler Martin

Abstract excerpt

Functionally different subsets of actin filament arrays contribute to cellular organization and motility. We report the identification of a novel subset of loose actin filament arrays through regulated association with the widely expressed protein SWAP-70. These loose actin filament arrays were commonly located behind protruding lamellipodia and membrane ruffles. Visualization of these loose actin filament arrays...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Minor Histocompatibility Antigens

Share to Myosins

Share to Phosphatidylinositol 3-Kinases

Share to Pseudopodia

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 12925760
DOI: 10.1091/mbc.e03-01-0043
PMCID: PMC181564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SWAP-70 identifies a transitional subset of actin filaments in motile cells.PMID 12925760Read ↗

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling.Semantic proximity Read ↗

SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration.Semantic proximity Read ↗

SWAP-70 is important for invasive phenotypes of mouse embryo fibroblasts transformed by v-Src.Semantic proximity Read ↗

SWAP-70: a new type of oncogene.Semantic proximity Read ↗

The Guanine Nucleotide Exchange Factor SWAP-70 Modulates the Migration and Invasiveness of Human Malignant Glioma CellsSemantic proximity Read ↗

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.Semantic proximity Read ↗

Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function.Semantic proximity Read ↗

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes.Semantic proximity Read ↗

A mutant of SWAP-70, a phosphatidylinositoltrisphosphate binding protein, transforms mouse embryo fibroblasts, which is inhibited by sanguinarine.Semantic proximity Read ↗

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.Semantic proximity Read ↗

Filopodia formation and endosome clustering induced by mutant plus-end-directed myosin VI.Semantic proximity Read ↗

Biased localization of actin binding proteins by actin filament conformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.