Article
SWAP-70 is important for invasive phenotypes of mouse embryo fibroblasts transformed by v-Src.
IUBMB life - 1 Apr 2008
Murugan Avaniyapuram Kannan, Ihara Sayoko, Tokuda Emi, Uematsu Kimio, Tsuchida Nobuo, Fukui Yasuhisa
Abstract excerpt
SWAP-70 is a protein involved in actin rearrangement, especially in membrane ruffling. Mouse embryo fibroblasts (MEFs) deficient in SWAP-70 show impaired membrane ruffling and fail to grow in soft agar after transformation by v-Src. Here, we show that v-Src transformed MEFs expressing SWAP-70 are...
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