Article
SWAP-70: a new type of oncogene.
PloS one - 1 Jan 2013
Shu Chung-Li, Jing-Yang-Lai, Su Liang-Cheng, Chuu Chih-Pin, Fukui Yasuhisa
Abstract excerpt
SWAP-70 is a protein that has been suggested to be involved in regulation of actin rearrangement. Having discovered that an artificially-derived mutant of SWAP-70 can transform mouse embryo fibroblasts, we searched for naturally-occurring mutations in the SWAP-70 gene, finding listings for several on the Web at www.sanger.ac.uk/genetics/CGP/cosmic/, including three mutations found in ovarian cancers. (The number...
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