Article
Association of Interleukin-10 promoter polymorphisms with neurosyphilis.
Human immunology - 1 Jul 2015
Pastuszczak Maciej, Jakiela Bogdan, Jaworek Andrzej Kazimierz, Wypasek Ewa, Zeman Jacek, Wojas-Pelc Anna
Abstract excerpt
Interleukin 10 (IL-10) is a potent anti-inflammatory cytokine. Increased production of IL-10 has been found in late syphilis, presumably creating favorable conditions for bacteria persistence. Single-nucleotide polymorphisms (SNPs) within the promoter of IL-10 gene have been found to influence IL-10 production. We investigated whether SNPs in the IL-10 gene promoter are associated with cerebrospinal fluid (CSF)...
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