Article
Interleukin-10 promoter polymorphisms and haplotypes in patients with Guillain-Barré syndrome.
Annals of clinical and translational neurology - 1 Jan 2024
Hayat Shoma, Asad Asaduzzaman, Munni Moriam Akter, Nayeem Md Abu Jaher, Mostafa Md Golam, Jahan Israt, Howlader Md Zakir Hossain, Mohammad Quazi Deen, Islam Zhahirul
Abstract excerpt
OBJECTIVE: Interleukin-10 (IL-10) is a multifunctional cytokine that exerts both pro- and anti-inflammatory effects on the immune system as well as in the pathogenesis of Guillain-Barré syndrome (GBS). We investigated whether the three common polymorphisms -1082 G/A(rs1800896), -819 C/T(rs1800871), and -592 C/A(rs1800872) in the promoter region of IL-10 have any influence on the susceptibility, severity, and...
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