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Article

Genetic association of IL-10 gene promoter polymorphism and HIV-1 infection in North Indians.

Journal of clinical immunology - 1 Jan 2009

Chatterjee Animesh, Rathore Anurag, Sivarama P, Yamamoto Naohiko, Dhole Tapan N

Abstract excerpt

INTRODUCTION: Cytokines play a significant role in host immune defense. IL-10 is an anti-inflammatory, immunomodulatory cytokine that can both stimulate and suppress the immune response and inhibits HIV-1 replication in vivo. Interindividual variations in IL-10 production were genetically contributed to polymorphisms within IL-10 promoter region. AIMS: The aim of this study was to investigate the association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18683035
DOI: 10.1007/s10875-008-9220-5

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