Article
Association of interleukin-10 gene promoter polymorphisms with susceptibility to acute pyelonephritis in children.
Folia microbiologica - 1 Jul 2014
Javor Juraj, Králinský Karol, Sádová Eva, Červeňová Oľga, Bucová Mária, Olejárová Michaela, Buc Milan, Liptáková Adriana
Abstract excerpt
Interleukin-10 (IL-10) is a potent inhibitor of leukocyte chemotaxis, bacterial killing in phagocytes and synthesis of pro-inflammatory cytokines and chemokines, and recent studies have suggested an important role for this immunoregulatory cytokine in the pathogenesis of urinary tract infections (UTIs). Therefore, the gene encoding IL-10 (IL10) is an attractive candidate for association studies attempting to...
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