Article
Interleukin-10 promoter polymorphisms in patients with Guillain-Barré syndrome.
Journal of neuroimmunology - 1 Jun 2003
Myhr K-M, Vågnes K S, Marøy T H, Aarseth J H, Nyland H I, Vedeler C A
Abstract excerpt
Interleukin-10 (IL-10) may have both pro- and anti-inflammatory effects in Guillain-Barré syndrome (GBS). The distribution of polymorphisms in the IL-10 gene (-1082 (G/A), -819 (T/C) and -592 (A/C)) was analysed to determine whether they could influence disease susceptibility or clinical course in GBS. The -592 CC and -819 CC genotypes associated with increased IL-10 response were more frequent in the GBS...
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