Article
Association of toll-like receptor 10 polymorphisms with pediatric pneumococcal meningitis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2020
Xiang Qiaoyan, Zhu Liang, Zheng Kai, Ding Yiwei, Chen Ning, Liu Gang, He Qiushui
Abstract excerpt
We aimed to investigate whether the gene polymorphisms of TLR10 were associated with risk and severity of pneumococcal meningitis (PM) and serum cytokine levels in children. Three single nucleotide polymorphisms (SNPs) of TLR10 rs4129009 (2676A > G), rs10004195 (1018T > A) and rs11466617 (40735A > G) were studied in 95 laboratory-confirmed PM pediatric patients and 330 healthy controls by PCR-based sequencing....
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