Article
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.
Gastroenterology - 1 Oct 2015
Zucman-Rossi Jessica, Villanueva Augusto, Nault Jean-Charles, Llovet Josep M
Abstract excerpt
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its mortality has increased in Western populations, with a minority of patients diagnosed at early stages, when curative treatments are feasible. Only the multikinase inhibitor sorafenib is available for the management of advanced cases. During the last 10 years, there has been a clear delineation of the landscape of genetic...
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