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Article

Genomic profiling in hepatocellular carcinoma: a real-world retrospective analysis

29 Oct 2025

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, with limited molecular characterization due to reliance on radiological diagnosis. This study aims to characterize the genomic landscape of advanced HCC and assess the prognostic and predictive roles of genetic alterations (GAs). PATIENTS AND METHODS: This study used a de-identified nationwide (USA-based) HCC...

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PMID: 41167083
DOI: 10.1016/j.esmoop.2025.105879

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