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Article

The pathogenesis of hepatocellular carcinoma.

Digestive diseases (Basel, Switzerland) - 1 Jan 2014

Kirstein Martha M, Vogel Arndt

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common and deadly malignancies worldwide. The multikinase inhibitor sorafenib still remains the only approved agent for advanced HCC. In most cases, HCC develops based on advanced liver cirrhosis, whereas the underlying risk factors can be identified in the vast majority of patients. METHODS: Here, we summarise and review the pathomechanisms in...

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Identifiers

PMID: 25034287
DOI: 10.1159/000360499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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