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Molecular Pathogenesis of Hepatocellular Carcinoma

8 Feb 2011

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the major causes of death among cirrhotic patients, being viral hepatitis and alcohol abuse, the main risk factors for its development. The introduction of highly sophisticated genomic technologies has spurred extensive research on the molecular pathogenesis of this devastating disease. Several signaling cascades have been consistently found dysregulated in HCC (e.g.,...

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PMID: 21303380
DOI: 10.1111/j.1530-0277.2010.01406.x

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