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CYP3A4 * 1G Genetic Polymorphism Influences Metabolism of Fentanyl in Human Liver Microsomes in Chinese Patients.

Pharmacology - 1 Jan 2015

Yuan Jing-Jing, Hou Jun-Kai, Zhang Wei, Chang Yan-Zi, Li Zhi-Song, Wang Zong-Yu, Du Ying-Ying, Ma Xiao-Jing, Zhang Li-Rong, Kan Quan-Cheng, Candiotti Keith A

Abstract excerpt

PURPOSE: This study aimed to investigate whether CYP3A4*1G genetic polymorphism influences the metabolism of fentanyl in human liver microsomes in Chinese patients. METHODS: The human liver microsomes were obtained from 88 hepatobiliary surgery patients who accepted liver resection surgery in this study. A normal liver sample (confirmed by the Department of Pathology) was taken from the outer edge of the resected...

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PMID: 26088794
DOI: 10.1159/000433441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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