Article
Effect of CYP3A4*18B polymorphisms and interactions with OPRM1 A118G on postoperative fentanyl requirements in patients undergoing radical gastrectomy.
Molecular medicine reports - 1 Mar 2013
Liao Qin, Chen Dao-Jin, Zhang Fan, Li Li, Hu Rong, Tang Yong-Zhong, Ou-Yang Wen, Huang Dong
Abstract excerpt
The present study aimed to investigate the effect of cytochrome P450 3A4 (CYP3A4)*18B polymorphisms and the interaction of the µ opioid receptor gene (OPRM1) A118G and CYP3A4*18B polymorphisms on postoperative fentanyl analgesia in Chinese Han patients undergoing radical gastrectomy. In total, 97 patients scheduled to undergo radical gastrectomy under general...
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