Article

Effect of CYP3A4 and CYP3A5 genetic polymorphism on individualized application of fentanyl in thoracoscopic surgery

2021-03-04

Abstract excerpt

<h4>Background: </h4> Studies have confirmed that CYP3A4 and CYP3A5 genotypes affect fentanyl metabolism in vivo. This study explores the application value of CYP3A4 and CYP3A5 genetic polymorphism in the individualized use of fentanyl in thoracoscopic surgery. Patients and Methods: One hundred American Society of Anesthesiologists physical status I or II patients, aged 40–65 years, with a body mass index of <30 k...

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Literature Corpus work: 0ec95f0b-a848-5e4b-95fc-96c4d2fc7b2a
DOI: 10.21203/rs.3.rs-267079/v1

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