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Article

CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients.

European journal of clinical pharmacology - 1 Jan 2010

Zhang Wei, Chang Yan-Zi, Kan Quan-Cheng, Zhang Li-Rong, Li Zhi-Song, Lu Hui, Wang Zhong-Yu, Chu Qin-Jun, Zhang Jie

Abstract excerpt

PURPOSE: To investigate whether the CYP3A4*1G genetic polymorphism contributes to the variability in CYP3A activity and response to fentanyl. METHODS: One hundred and forty-three gynecologic patients who were scheduled to undergo abdominal total hysterectomy or myomectomy with general anesthesia were enrolled in this study. Intravenous fentanyl patient-controlled analgesia was provided postoperatively for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19784640
DOI: 10.1007/s00228-009-0726-4

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