Article
Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice.
Thrombosis and haemostasis - 1 Oct 2015
Selle Jaco, Asare Yaw, Köhncke Janine, Alampour-Rajabi Setareh, Shagdarsuren Gansuvd, Klos Andreas, Weber Christian, Jankowski Joachim, Shagdarsuren Erdenechimeg
Abstract excerpt
Atherogenic processes and vascular remodelling after arterial injury are controlled and driven by a plethora of factors amongst which the activation of the complement system is pivotal. Recently, we reported a clear correlation between high expressions of the second receptor for complement anaphylatoxin C5a, the C5a receptor-like 2 (C5L2, C5aR2), with high pro-inflammatory cytokine expression in advanced human...
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