Article
Protective Role of C3aR (C3a Anaphylatoxin Receptor) Against Atherosclerosis in Atherosclerosis-Prone Mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2020
Wei Lin-Lin, Ma Ning, Wu Kun-Yi, Wang Jia-Xing, Diao Teng-Yue, Zhao Shu-Juan, Bai Liang, Liu Enqi, Li Zong-Fang, Zhou Wuding, Chen Daxin, Li Ke
Abstract excerpt
OBJECTIVE: Emerging evidence suggests that C3aR (C3a anaphylatoxin receptor) signaling has protective roles in various inflammatory-related diseases. However, its role in atherosclerosis has been unknown. The purpose of the study was to investigate the possible protective role of C3aR in aortic atherosclerosis and explore molecular and cellular mechanisms involved in the protection. Approach and Results:...
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