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IgRepertoireConstructor: a novel algorithm for antibody repertoire construction and immunoproteogenomics analysis

10 Jun 2015

Abstract excerpt

UNLABELLED: The analysis of concentrations of circulating antibodies in serum (antibody repertoire) is a fundamental, yet poorly studied, problem in immunoinformatics. The two current approaches to the analysis of antibody repertoires [next generation sequencing (NGS) and mass spectrometry (MS)] present difficult computational challenges since antibodies are not directly encoded in the germline but are...

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PMID: 26072509
DOI: 10.1093/bioinformatics/btv238

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