RIOT - Rapid Immunoglobulin Overview Tool - annotation of nucleotide and amino acid immunoglobulin sequences using an open germline database.

Abstract excerpt

Antibodies are a cornerstone of the immune system, playing a pivotal role in identifying and neutralizing infections caused by bacteria, viruses, and other pathogens. Understanding their structure, and function, can provide insights into both the body's natural defenses and the principles behind many therapeutic interventions, including vaccines and antibody-based drugs. The analysis and annotation of antibody seq...

Topics

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• Algorithms
• Computer Simulation
• Databases, Genetic
• Glycosylation and Glycoproteins Research
• Monoclonal and Polyclonal Antibodies Research
• RNA and protein synthesis mechanisms
• T-cell and B-cell Immunology
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

07456354-dd2e-5e35-9120-cdb3ec22beda

DOI

10.1101/2024.08.12.607568