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Reconstructing and mining the B cell repertoire with ImmunediveRsity

15 Apr 2015

Abstract excerpt

The B cell antigen receptor repertoire is highly diverse and constantly modified by clonal selection. High-throughput DNA sequencing (HTS) of the lymphocyte repertoire (Rep-Seq) represents a promising technology to explore such diversity ex-vivo and assist in the identification of antigen-specific antibodies based on molecular signatures of clonal selection. Therefore, integrative tools for repertoire...

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PMID: 25875140
DOI: 10.1080/19420862.2015.1026502

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