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Resistance to pyrazinamide in Russian Mycobacterium tuberculosis isolates: pncA sequencing versus Bactec MGIT 960.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2015

Maslov Dmitry A, Zaĭchikova Marina V, Chernousova Larisa N, Shur Kirill V, Bekker Olga B, Smirnova Tatiana G, Larionova Elena E, Andreevskaya Sofya N, Zhang Ying, Danilenko Valery N

Abstract excerpt

Resistance to pyrazinamide (PZA) may impact clinical outcome of anti-tuberculosis chemotherapy. PZA susceptibility testing using MGIT 960 is not reliable and little information is available on the prevalence of PZA resistance in Russia. A collection of 64 clinical isolates of Mycobacterium tuberculosis, including 35 multidrug resistant and extensively drug-resistant (MDR/XDR), was analyzed for PZA resistance...

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Identifiers

PMID: 26071666
DOI: 10.1016/j.tube.2015.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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