Article
Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Zhejiang, China.
Antimicrobial agents and chemotherapy - 1 Mar 2015
Xia Qiang, Zhao Li-Li, Li Feng, Fan Yu-Mei, Chen Yuan-Yuan, Wu Bei-Bei, Liu Zheng-Wei, Pan Ai-Zhen, Zhu Min
Abstract excerpt
To explore the phenotypic and genotypic characterization of pyrazinamide (PZA) resistance among multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates in Zhejiang province, a total of 274 MDR-TB isolates were collected. Drug susceptibility testing and spoligotyping were performed on all clinical isolates. In addition, the mutated features of PZA-resistant loci, including pncA and rpsA, were also...
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