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Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

1 Aug 2020

Abstract excerpt

Purpose: This study was designed to identify the phenotypic and genotypic characteristics of pyrazinamide (PZA) resistance among multidrug-resistant Mycobacterium tuberculosis (MDR-TB) from Henan and to evaluate the efficacy of pncA, rpsA , and panD mutations in predicting PZA resistance. Materials and Methods: A total of 152 MDR strains were included in this study. The Bactec MGIT system was used to determine...

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PMID: 32903869
DOI: 10.2147/idr.s260161

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