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Article

Genotypic characterization of pyrazinamide resistance in Mycobacterium tuberculosis isolated from Lusaka, Zambia.

Tuberculosis (Edinburgh, Scotland) - 1 Mar 2018

Bwalya Precious, Yamaguchi Tomoyuki, Mulundu Georgina, Nakajima Chie, Mbulo Grace, Solo Eddie Samuneti, Fukushima Yukari, Kasakwa Kunda, Suzuki Yasuhiko

Abstract excerpt

Pyrazinamide forms a core part of treatment for all types of tuberculosis (TB) in Zambia. Due to challenges associated with pyrazinamide testing, little information is available to indicate the frequency of resistance to this drug in Zambia. To determine the frequency of pyrazinamide (PZA) resistance and its correlation with mutation in pncA in Mycobacterium tuberculosis isolated from patients in Lusaka, Zambia,...

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Identifiers

PMID: 29559115
DOI: 10.1016/j.tube.2017.12.007

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