Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.

Scientific reports - 5 Jun 2015

Jeon Young Joo, Kim Jong Woo, Park Hye Mi, Kim Jung O, Jang Hyo Geun, Oh Jisu, Hwang Seong Gyu, Kwon Sung Won, Oh Doyeun, Kim Nam Keun

Abstract excerpt

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) play important roles in tumor development, progression, and metastasis. Moreover, recent studies have reported that a number of 3'-UTR polymorphisms potentially bind to specific microRNAs in a variety of cancers. The aim of this study was to investigate the association of four MTHFR polymorphisms, 2572C>A [rs4846049], 4869C>G [rs1537514], 5488C>T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to 3' Untranslated Regions
Share to Adenocarcinoma
Share to Colorectal Neoplasms
Share to Folic Acid
Share to Genetic Association Studies
Share to Homocysteine
Share to Methylenetetrahydrofolate Reductase (NADPH2)
Share to Republic of Korea

Source

Open in PubMed Open full text

Identifiers

PMID: 26046315
DOI: 10.1038/srep11006
PMCID: PMC4457011

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.PMID 26046315Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer.Semantic proximity Read ↗

Contribution of 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase Genotypes to Colorectal Cancer in Taiwan.Semantic proximity Read ↗

The 677C>T (rs1801133) polymorphism in the MTHFR gene contributes to colorectal cancer risk: a meta-analysis based on 71 research studies.Semantic proximity Read ↗

MTHFR C677T polymorphism contributes to colorectal cancer susceptibility: evidence from 61 case-control studies.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and fluorouracil-based treatment in Taiwan colorectal cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase genotypes and haplotypes associated with susceptibility to colorectal cancer in an eastern Chinese Han population.Semantic proximity Read ↗

Evaluation of the MTHFR C677T Polymorphism as a Risk Factor for Colorectal Cancer in Asian Populations.Semantic proximity Read ↗

5,10-Methylenetetrahydrofolate reductase polymorphisms and colon cancer risk: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms of methylenetetrahydrofolate reductase and susceptibility to colorectal cancer.Semantic proximity Read ↗

Association of the 677C -->T polymorphism in the MTHFR gene with colorectal cancer in Mexican patients.Semantic proximity Read ↗

Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.