Article
Association of the 677C -->T polymorphism in the MTHFR gene with colorectal cancer in Mexican patients.
Cancer genomics & proteomics - 1 Jan 2000
Gallegos-Arreola M P, García-Ortiz J E, Figuera L E, Puebla-Pérez A M, Morgan-Villela G, Zúñiga-González G M
Abstract excerpt
The 5,10-methyl-tetrahydrofolate reductase (MTHFR) enzyme plays a critical role in folate and homocysteine metabolism, and its gene, MTHFR, displays common genetic polymorphisms that influence its activity. Clinical implications of MTHFR polymorphisms have been reported for several diseases, incl...
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