Article
Genetic polymorphisms of methylenetetrahydrofolate reductase and susceptibility to colorectal cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Cao Hai-Xia, Gao Chang-Ming, Takezaki Toshiro, Wu Jian-Zhong, Ding Jian-Hua, Liu Yan-Ting, Li Su-Ping, Su Ping, Cao Jia, Hamajima Nobuyuki, Tajima Kazuo
Abstract excerpt
OBJECTIVES: To study the relation between genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) C677T or A1298C and the susceptibility of colorectal cancer. METHODS: We conducted a case-control study with 315 cases of colorectal cancer and 371 population-based controls in Jiangsu province, China. The epidemiological data were collected, and DNA of peripheral blood leukocytes was obtained from all...
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