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Article

Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis.

Bioscience reports - 22 Dec 2017

Xu Lingyan, Qin Zhiqiang, Wang Feng, Si Shuhui, Li Lele, Lin Peinan, Han Xiao, Cai Xiaomin, Yang Haiwei, Gu Yanhong

Abstract excerpt

The association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer (CRC) susceptibility has been researched in numerous studies. However, the results of these studies were controversial. Therefore, the objective of this meta-analysis was to offer a more convincible conclusion about such association with more included studies. Eligible studies published till May 1, 2017...

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Source

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Identifiers

PMID: 29089462
DOI: 10.1042/BSR20170917
PMCID: PMC5719002

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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