Article
Contribution of 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase Genotypes to Colorectal Cancer in Taiwan.
Anticancer research - 1 May 2022
Wu Ming-Hsien, Chen Chao-Hsuan, Chen Chou-Pin, Huang Tai-Lin, Yueh Te-Cheng, Wang Zhi-Hong, Tsai Chia-Wen, Pei Jen-Sheng, Mong Mei-Chin, Yang Ya-Chen, Bau DA-Tian, Chang Wen-Shin
Abstract excerpt
BACKGROUND/AIM: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) is responsible for folate metabolism, and we aimed to investigate its genetic role in colorectal cancer (CRC) among Taiwanese. MATERIALS AND METHODS: A total of 362 cases and 362 controls were recruited and their MTRR rs1801394 (A66G) and rs1532268 (C524T) genotypes were examined. The behavioral factors and...
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