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Article

COMT genotype, gambling activity, and cognition.

Journal of psychiatric research - 1 Sept 2015

Grant Jon E, Leppink Eric W, Redden Sarah A, Odlaug Brian L, Chamberlain Samuel R

Abstract excerpt

Neuropsychological studies of adults with problem gambling indicate impairments across multiple cognitive domains. Catechol-O-methyltransferase (COMT) plays a unique role in the regulation of dopamine in the prefrontal cortex, and has been implicated in the cognitive dysfunction evident in problem gambling. This study examined adults with varying levels of gambling behavior to determine whether COMT genotype was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26028545
DOI: 10.1016/j.jpsychires.2015.04.029

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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