Association of the COMT Met¹⁵⁸ allele with trait impulsivity in healthy young adults.

doi:10.3892/mmr.2013.1336

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Article

Association of the COMT Met¹⁵⁸ allele with trait impulsivity in healthy young adults.

Molecular medicine reports - 1 Apr 2013

Soeiro-De-Souza Márcio Gerhardt, Stanford Matthew S, Bio Danielle Soares, Machado-Vieira Rodrigo, Moreno Ricardo Alberto

Abstract excerpt

Dopamine (DA) is considered to be an important neurotransmitter in the control of impulsive behavior, however, its underlying mechanisms have not been fully elucidated. Catechol-O-methyltransferase (COMT) is a key enzyme in the catabolism of DA within the prefrontal cortex (PFC) and has been suggested to play a role in the mediation of impulsive behavior. The COMT single nucleotide polymorphism (SNP) rs4680...

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Identifiers

PMID: 23440431
DOI: 10.3892/mmr.2013.1336

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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