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Article

An integrated genotyping approach for HLA and other complex genetic systems.

Human immunology - 1 Dec 2015

Nelson Wyatt C, Pyo Chul-Woo, Vogan David, Wang Ruihan, Pyon Yoon-Soo, Hennessey Carly, Smith Anajane, Pereira Shalini, Ishitani Akiko, Geraghty Daniel E

Abstract excerpt

Clinical immunogenetics laboratories performing routine sequencing of human leukocyte antigen (HLA) genes in support of hematopoietic cell transplantation are motivated to upgrade to next-generation sequencing (NGS) technology by its potential for cost savings as well as testing accuracy and flexibility. While NGS machines are available and simple to operate, there are few systems available that provide...

Topics

Alleles
Computational Biology
Exons
Genotype
Genotyping Techniques
HLA Antigens
Haplotypes
High-Throughput Nucleotide Sequencing
Histocompatibility Testing
Humans
Reproducibility of Results

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Software

Workflow

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Identifiers

PMID: 26027777
DOI: 10.1016/j.humimm.2015.05.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26027777-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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