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Article

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.

Genome biology - 30 May 2015

Strogantsev Ruslan, Krueger Felix, Yamazawa Kazuki, Shi Hui, Gould Poppy, Goldman-Roberts Megan, McEwen Kirsten, Sun Bowen, Pedersen Roger, Ferguson-Smith Anne C

Abstract excerpt

BACKGROUND: Selective maintenance of genomic epigenetic imprints during pre-implantation development is required for parental origin-specific expression of imprinted genes. The Kruppel-like zinc finger protein ZFP57 acts as a factor necessary for maintaining the DNA methylation memory at multiple imprinting control regions in early mouse embryos and embryonic stem (ES) cells. Maternal-zygotic deletion of ZFP57 in...

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Identifiers

PMID: 26025256
DOI: 10.1186/s13059-015-0672-7
PMCID: PMC4491874

Genes

ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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