Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteins involved in establishment and maintenance of imprinted methylation marks

1 May 2012

Abstract excerpt

Epigenetic phenomena are being increasingly recognized to play key roles in normal mammalian development and disease. This is exemplified by the process of genomic imprinting whereby despite identical DNA sequence, the two parental chromosomes are not equivalent and show either maternal- or paternal-specific expression at a subset of genes in the genome. These patterns are set up by differential DNA methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22760206
DOI: 10.1093/bfgp/els018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteins involved in establishment and maintenance of imprinted methylation marksPMID 22760206Read ↗

Should I stay or should I go: Protection and maintenance of DNA methylation at imprinted genesSemantic proximity Read ↗

The specification of imprints in mammalsSemantic proximity Read ↗

The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances.Semantic proximity Read ↗

Human and mouse ZFP57 proteins are functionally interchangeable in maintaining genomic imprinting at multiple imprinted regions in mouse ES cells.Semantic proximity Read ↗

In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control RegionsSemantic proximity Read ↗

Zinc finger protein ZFP57 requires its co-factor to recruit DNA methyltransferases and maintains DNA methylation imprint in embryonic stem cells via its transcriptional repression domain.Semantic proximity Read ↗

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.Semantic proximity Read ↗

Genomic imprinting: the influence of differential methylation in the two sexesSemantic proximity Read ↗

Epigenetic regulation of unique genes and repetitive elements by the KRAB zinc finger protein ZFP57Semantic proximity Read ↗

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.Semantic proximity Read ↗

A KRAB domain zinc finger protein in imprinting and disease.Semantic proximity Read ↗

DNA methylation, chromatin boundaries, and mechanisms of genomic imprinting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.