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Article

Fine mapping genetic determinants of the highly variably expressed MHC gene ZFP57.

European journal of human genetics : EJHG - 1 Apr 2014

Plant Katharine, Fairfax Benjamin P, Makino Seiko, Vandiedonck Claire, Radhakrishnan Jayachandran, Knight Julian C

Abstract excerpt

ZFP57 is an important transcriptional regulator involved in DNA methylation and genomic imprinting during development. Here we demonstrate that gene expression also occurs at a low level in adult peripheral blood cells and other tissues including the kidney and thymus, but is critically dependent on underlying local genetic variation within the MHC. We resolve a highly significant expression quantitative trait...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24193346
DOI: 10.1038/ejhg.2013.244
PMCID: PMC3953924

Genes

ZFP57
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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