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Article

Genomic imprinting defect in Zfp57 mutant iPS cell lines.

Stem cell research - 1 Mar 2016

McDonald Carol M, Liu Lizhi, Xiao Lijuan, Schaniel Christoph, Li Xiajun

Abstract excerpt

ZFP57 maintains genomic imprinting in mouse embryos and ES cells. To test its roles during iPS reprogramming,we derived iPS clones by utilizing retroviral infection to express reprogramming factors in mouse MEF cells. After analyzing four imprinted regions, we found that parentally derived DNA methylation imprint was largely maintained in the iPS clones with Zfp57 but missing in those without maternal or zygotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27252991
DOI: 10.1016/j.scr.2016.01.018
PMCID: PMC4891939

Genes

ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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