Article
High-resolution melting analysis of single nucleotide polymorphisms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Bruzzone Carol M, Steer Clifford J
Abstract excerpt
The technology of Single Nucleotide Polymorphism (SNP) detection has evolved steadily through mobility shift studies, mass cleavage product evaluations, heterodimer differences in chemical, conformational, and enzymatic properties, mass spectroscopy and sequencing, to allele-specific hybridization probe methods. Each method presented challenges of labor intensity, unreliable efficiencies, complicated...
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