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Article

High resolution melting applications for clinical laboratory medicine.

Experimental and molecular pathology - 1 Aug 2008

Erali Maria, Voelkerding Karl V, Wittwer Carl T

Abstract excerpt

Separation of the two strands of DNA with heat (melting) is a fundamental property of DNA that is conveniently monitored with fluorescence. Conventional melting is performed after PCR on any real-time instrument to monitor product purity (dsDNA dyes) and sequence (hybridization probes). Recent advances include high resolution instruments and saturating DNA dyes that distinguish many different species. For...

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Identifiers

PMID: 18502416
DOI: 10.1016/j.yexmp.2008.03.012
PMCID: PMC2606052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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