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Article

TP53: an oncogene in disguise.

Cell death and differentiation - 1 Aug 2015

Soussi T, Wiman K G

Abstract excerpt

The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. However, it is now an indisputable fact that many p53 mutants act as oncogenic proteins. This statement is based on multiple arguments including the mutation signature of the TP53 gene in human cancer, the various gains-of-function (GOFs) of the different p53 mutants and...

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Source

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Identifiers

PMID: 26024390
DOI: 10.1038/cdd.2015.53
PMCID: PMC4495363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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