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Article

Combined ATRX/IDH1 immunohistochemistry predicts genotype of oligoastrocytomas.

Histopathology - 1 Jan 2016

Hewer Ekkehard, Vajtai Istvan, Dettmer Matthias S, Berezowska Sabina, Vassella Erik

Abstract excerpt

AIMS: To assess whether in oligoastrocytomas ATRX deficiency, as a surrogate of the alternative lengthening of telomeres (ALT) pathway, has a role in predicting the presence or absence of loss of heterozygosity (LOH) of 1p and 19q, the genetic signature of oligodendroglial differentiation and a favourable prognostic marker. METHODS AND RESULTS: A series of 54 oligoastrocytomas were investigated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26016385
DOI: 10.1111/his.12743

Genes

ATRX
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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