Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATRX loss in glioneuronal tumors with neuropil-like islands indicates similarity to diffuse astrocytic tumors.

Journal of neuro-oncology - 1 Oct 2016

Kakkar Aanchal, Nambirajan Aruna, Kaur Kavneet, Kumar Anupam, Mallick Supriya, Suri Vaishali, Sarkar Chitra, Kale Shashank Sharad, Garg Ajay, Sharma Mehar Chand

Abstract excerpt

Glioneuronal tumor with neuropil-like islands (GTNI) is a rare, recently described neoplasm, whose pathogenesis has not been studied extensively. The role of ATRX mutations, a class-defining alteration in diffuse astrocytic neoplasms, has not been assessed in GTNIs previously. We therefore aimed to assess the status of ATRX, along with IDH1, 1p/19q and p53, in cases of GTNI in order to evaluate the molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Glial Fibrillary Acidic Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to Magnetic Resonance Imaging

Share to Phosphopyruvate Hydratase

Share to Tumor Suppressor Protein p53

Share to X-linked Nuclear Protein

Source

Identifiers

PMID: 27469217
DOI: 10.1007/s11060-016-2224-8

Genes

ATRX
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATRX loss in glioneuronal tumors with neuropil-like islands indicates similarity to diffuse astrocytic tumors.PMID 27469217Read ↗

ATRX in Diffuse Gliomas With its Mosaic/Heterogeneous Expression in a Subset.Semantic proximity Read ↗

Utility of ATRX immunohistochemistry in diagnosis of adult diffuse gliomas.Semantic proximity Read ↗

ATRX loss in adult supratentorial diffuse astrocytomas correlates with p53 over expression and IDH1 mutation and predicts better outcome in p53 accumulated patients.Semantic proximity Read ↗

IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas.Semantic proximity Read ↗

Molecular Classification Defines 4 Prognostically Distinct Glioma Groups Irrespective of Diagnosis and GradeSemantic proximity Read ↗

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.Semantic proximity Read ↗

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations.Semantic proximity Read ↗

Practice of IDH1, ATRX, and P53 Immunohistochemistry in Integrated Diagnosis of Adult Diffuse Gliomas: Single Center Study.Semantic proximity Read ↗

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples.Semantic proximity Read ↗

Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusionsSemantic proximity Read ↗

The Role of ATRX in Glioma BiologySemantic proximity Read ↗

Cellular and molecular characterization of IDH1-mutated diffuse low grade gliomas reveals tumor heterogeneity and absence of EGFR/PDGFRα activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.