Article
A dual-genotype oligoastrocytoma with histologic, molecular, radiological and time-course features.
Acta neuropathologica communications - 20 Jul 2020
Nasrallah Mac Lean P, Desai Arati, O'Rourke Donald M, Surrey Lea F, Stein Joel M
Abstract excerpt
A case of a true dual-genotype IDH-mutant oligoastrocytoma with two different cell types within a single mass in a young woman is presented. Imaging findings of the left frontal infiltrating glioma predicted the two neoplastic components that were identified upon resection. Tissue examination demonstrated areas of tumor with contrasting histologic and molecular features, including specific IDH1, ATRX, TP53, TERT...
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